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DERMOPURE Adjunctive Soothing Cream

Soothes skin under medical acne treatment
Intensively moisturises and reduces dryness
Calms skin irritation and redness

Soothes skin under medical acne treatment

A cream that alleviates the side effects of acne medication. Soothes irritations, reduces tightness and helps you to regain control over demanding blemish-prone skin.

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Product Info

Moisturizer for acne-prone skin

Eucerin DERMOPURE Adjunctive Soothing Cream is a moisturizer for acne-prone skin specially formulated for people undergoing medical acne treatment.

One of the side effects of acne medication is that it frequently causes severe dryness in skin. This intensely moisturising, non-greasy cream soothes these symptoms. Ceramides support skin’s protective barrier and reduce moisture loss, SymSitive* helps to calm irritation such as stinging and burning directly at source and Licochalcone A helps to reduce redness. The formula helps to bring demanding, blemish- and acne-prone skin under control and it feels smooth and supple after the first application.

* Registered trademark of Symrise AG, Germany

Clinical and dermatological studies

Good skin tolerability and efficacy on blemish-prone skin. Suitable for sensitive skin.

Main findings


of dermatologists would recommend as adjunctive care for their acne patiets


skin feels comfortable after regular application


silky smooth texture


reduces feelings of tightness


soothes skin under medical acne treatment


alleviates side-effects of acne treatment


alleviates stinging and burning


skin feels softer after the first application

In a self-assessment study a sample of 58 men and women aged between 16 and 43 (average age 24) applied Eucerin DERMOPURE Adjunctive Soothing Cream twice a day for two weeks. At the time of the study, all respondents had been undergoing medical acne treatment (with topical Benzoyl Peroxide, topical Tretinoin, topical Adapalene or oral Isotretinoin) for at least two weeks.

How to use


  • Use daily in the morning and/or in the evening – as often as necessary
  •  Apply a chickpea-sized amount to a thoroughly cleansed face (try Eucerin DERMOPURE Cleansing Gel)
  • Massage gently
  • Avoid contact with your eyes
  • Follow with an appropriate sun protection product such as Eucerin Sun Gel-Creme Oil Control Dry Touch SPF30 or 50+. This is important to help prevent pigmentation issues in blemish-prone skin
  • Eucerin DERMOPURE Adjunctive Soothing Cream is an excellent base for make-up

Recommendations for your daily skincare routine

Cleanse and tone

Cleanse skin in the morning and evening:

  • am: to remove the sebum and dead skin cells that have accumulated overnight
  • pm: to remove make-up and free skin from the day’s dirt

Use gentle cleansing products such as Eucerin DERMOPURE Cleansing Gel with lukewarm water and follow with an appropriate toner. You may also benefit from using a scrub once a week to unclog pores and refine skin texture.

We do not recommend using an alcohol-based toner and the scrub alongside acne medication as it can make skin more sensitive. If you like the refreshing feel of a toner, try the alcohol-free Eucerin DERMOPURE Micellar Water instead.

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The care product you use depends on the severity of your acne and on the type of treatment you are undergoing.


If you are using medical treatment for acne, Eucerin DERMOPURE Adjunctive Soothing Cream helps to alleviate some of the symptoms such as intense dryness. It should be applied five minutes after your medication so the treatment can absorb fully.


If you have mild to moderate acne, but are not undergoing medical acne treatment, use a soothing and mattifying moisturiser such as Eucerin DERMOPURE Mattifying Fluid in the morning and evening.


For clearer and smoother-looking skin over time, you may also like to incorporate our skin renewal treatment into your routine. It is suitable for all blemish-prone skin that is not undergoing medical acne treatment and should be used once a day only − ideally in the evening. You can use it before the mattifying fluid or on its own.

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Sun protection

Sun protection is an important step in your morning routine. Blemishes can cause pigmentation issues if over-exposed to the sun, and acne medications can make blemish-prone skin even more sensitive to UV rays. Eucerin Sun Gel-Creme Oil Control Dry Touch SPF30 and SPF50+ offers the levels of protection that your skin needs and should be applied before your cover-up and make-up. If you’re applying sun protection after a topical acne treatment wait five minutes to allow the treatment to fully absorb. 

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Concealer and make-up

Cover blemishes and even out skin tone with foundation and/or a concealer. Choose products that are non-comedogenic (i.e. that will not block pores) and, ideally, ones that contain ingredients that work to improve the condition of blemish-prone skin. Be sure to remove all make-up before you go to bed.

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How Eucerin DERMOPURE Adjunctive Soothing Cream works

Many patients undergoing medical acne therapy experience side effects such as dryness, redness, hypersensitivity (stinging and burning) and photosensitivity (sensitivity to sunlight). These common symptoms are uncomfortable to live with and can cause people to stop treatment before it is complete.

The active ingredients in Eucerin DERMOPURE Adjunctive Soothing Cream work to reduce many of these symptoms so that people can continue with their treatment without discomfort:

  •  Improves skin hydration: the formula intensely moisturises skin and the Ceramides strengthen skin’s own protective barrier to prevent moisture loss
  • Reduces redness: Licochalcone A is a powerful anti-inflammatory ingredient that helps reduce redness
  • Soothes sensitivity: SymSitive* gets to the root causes of sensitivity by reducing the responsiveness of the nerve fibres

We recommend that people undergoing medical acne therapy also apply a high sun protection factor product (such as Eucerin Sun Gel-Creme Oil Control Dry Touch SPF30 or SPF50+) as skin is particularly sensitive to sunlight. This will help to reduce photosensitivity and protect acne-prone skin from the pigmentation issues that UV rays can cause.

* registered trademark of Symrise AG, Germany

Moisutrisation/barrier strengthening

Formula: Intensive moisturisation of dehydrated skin

Ceramides: Strengthen skin’s protective barrier and reduce moisture loss


Licochalcone A: An anti-inflammatory that helps reduce redness


SymSitive*: Soothes irritation directly at source by reducing the responsiveness of nerve fibres


Eucerin Sun Gel-Creme Oil Control Dry Touch: specially developed for acne-prone skin with a UVA/UVB filter system and biological cell protection.

* registered trade mark of Symrise AG, Germany

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Our brand values

Pioneers in skincare

We deliver a holistic dermo-cosmetic approach to protect your skin, keep it healthy and radiant.

Recommended by dermatologists

We work together with leading dermatologist and pharmacist partners around the world to create innovative and effective skincare products they can trust and recommend.

Committed to innovation

For over 100 years, we have dedicated ourselves to researching and innovating in the field of skin science. We believe in creating active ingredients and soothing formulas with high tolerability that work to help you live your life better each day.